From the direction of Eunos Link, Hougang Ave 3 and Hougang Ave 2, you can take bus number 25. Alight at the bus stop in front of Blk 452.
From Ang Mo Kio MRT station, take Exit A and take either bus number 25, 73, 74, 88, 132, 165, 261 or 268. Alight at the second stop. You can either cross the overhead bridge or use the traffic light, then you will reach Block 452.